Muviri wemunhu inoshamisa, inoshamisa. Pasinei nemazana emakore-nhoroondo yezvemishonga, kusvikira zvino, zvese zvinoshandiswa uye simba remuviri womunhu hazvina kunyatsodzidza. Mahomoni ndiyo imwe yenzira dzakasimba zvikuru dzekuzvitonga kwemuviri, uye munyaya ino tichataura pamusoro peumwe wavo - androstenedione. Kunyanya zvakanyatsoitika, pamusoro pezvinoratidzwa nepamusoro ye androstenedione, nzira yekuderedza androstenedione, uye kana zvakakosha kuzvidya mwoyo kana kuongororwa kwe laboratori kwakaratidza kuti hormone androstenedione yakakwirira mukati mako.
Chii Androstenedione chinotarisirwa?
Androstenedione ndiyo hormone ye adrenals uye gonads. Iyo inobudiswa mumuviri wevarume nevakadzi. Icho chisingaenderani nechokuita nekuvandudzirwa kwemadzimai evanhukadzi nevakadzi, kunyanya estrogen uye testosterone. Nhamba yakakwana yehomoni iyi muropa inobvumira chiropa nemafuta matema kuti aite zvekuita mahara hormone.
Nhamba ye androstenedione inotanga kuwedzera zvakanyanya kubva makore 7-8. Mushure mekusvika kumunhu wemakore makumi matatu, kufambisa kwehomoni iyi inotanga kuwedzera zvishoma nezvishoma.
Androstenedione: chimiro chevakadzi nevarume
Izvo zvakaenzana nehuwandu hwe androstenedione muropa, zvichienderana nezera remunhu:
- vana 1-7 mazuva mushure mekuberekwa - 20-290 ng / 100ml;
- Vana vacheche (mwedzi 1-12) - 6-68 ng / 100ml;
- vana vane makore 1-10 - 8-50 ng / 100ml;
- vechidiki (10-17) - 8-240 ng / 100ml;
- varume - 75-205 ng / 100ml;
- vakadzi - 85-275 ng / 100ml.
Kuparadzana kunoonekwa kubva pamusana wepamusoro we androstenedione kunogona kuonekwa nekudyiwa kwemishonga yeHodmon, tumoramu etiologies dzakasiyana uye mune dzimwe zvirwere.
Androstenedion akakwirira: zvinokonzera
Zvinokonzera kuwedzerwa maitiro e androstenedione kunogona kunge iri dambudziko mumutambo weAdrenal uye / kana ovarian. Kazhinji kacho, kuwedzera kwehuwandu hwe androstenedione kunoratidza zvirwere zvakadaro:
- polycystic ovary;
- hyperplasia ye adrenal cortex;
- iyo Itenko-Cushing syndrome;
- female osteoporosis;
- stromal hypertecosis ye maovari;
- matumbo evhavari yezvakasiyana-siyana uye zvimwe zvirwere.
Nhamba yakaderedzwa ye androstenedione inowanikwa mukusina kweivhai kana adrenal cortex.
Zvichienderana nezvenguva yemazuva, chikamu chekuenda kumwedzi, uye andststoneone level yakasiyana. Mizinga yakakwirira inowanikwa mumangwanani emaawa, uye pakati pekuenda kumwedzi kune vakadzi. Panguva yekuzvitakura, uwandu hwehomoni iyi hunowedzerawo.
Androstenedione yakakwirira: zviratidzo
Kana androstenedione muvakadzi yakasimudzwa, kazhinji kacho kune kukanganiswa kwebvudzi rakawandisa (hirsutism), kurwisa syndrome. Kuwedzera kwehuwandu hwehomoni iyi kunogonawo kukonzera kuberekwa kwepakutanga, uterine kubuda ropa, marudzi akasiyana-siyana ekusavhiringidza mumabasa ekubereka kwemuviri mushure mekupedzisira kwehuwandu husina kuenzana kwehomoni.
Zvinotendwa kuti kuwedzera kwe androstenedione kunokonzera kuwedzera nokukurumidza musimba mashoma, ndicho chikonzero iyi hormone uye kugadzirira iripo iyo inonyanya kuzivikanwa pakati pevarimi vemiti, kunyange zvazvo isina vanabolic effect. Panguva iyi, zvinokuvadza kubva kushandiswa zvisina kudzora kwemishonga yakadaro pane dzimwe nguva zvinodarika zvinoita kuti zvive nemigumisiro yakanaka yekushandiswa kwayo - kurara, kuwedzera kweprostate, kuputsa kwehutano hwemuviri (somuenzaniso, kukura kwevarume muvarume), bvudzi rakawandisa pamuviri - iyo iri kure nemabhuku akazara emigumisiro yaro kusagadziriswa kugamuchirwa.
Androstenedione yakakwirira: kurapwa
Kana iyo level androstenedione yakakwirira mumadzimai, kurapwa kunowanzodiwa. Kuti uongorore uye urongedze kurapa kwakakwana, unofanirwa kuonana ne-endocrinologist uye gynecologist (yevakadzi) kana kuti androlog (yevarume).
Iyo inonyanya kushandiswa: dexamethasone, clomiphene, dzakasiyana-siyana zvekudzivirira vana. Mishonga yekurapa, urongwa hwezvinodhaka uye nzira dzokurapa dzinosiyana zvikuru zvichienderana nezvinokonzera uye chimiro chechinetso, kuvapo kwezvirwere zvinokonzera, nguva uye zvakazara murwere. Kuzvibata hakubvumirwi zvachose. Zvose zvinodhaka zvinodhaka zvinofanira kunyoreswa chete neyanyanzvi anoziva.