Chimwe chezvikonzero zvinowanzoita zvekushaya vana ndiyo hyperandrogenism kuvakadzi - chirwere chemagumo endocrine. Izvi zvinowanikwa muvakadzi vanopfuura 20%.
Hyperandrogenism muvakadzi - inokonzera
Hyperandrogenia muvakadzi inokonzera zvirwere zve endocrine, pamwe nemakumbo emagumo endocrine - pituitary (senhengo ye hypothalamic-pituitary system), thymus, thyroid, pancreas, adrenals uye gonads). Uyewo, chinokonzera kuwanda kwemahomoni evanhu - androgens - is adrenogenital syndrome. Nhamba yakawanda yemhomoni yevarume inoshandurwa kuva glucocorticoids pasi pekuita kweine enzyme chaiyo, iyo yakagadzirwa inogadziriswa yakarongwa. Chimwe chikonzero che hyperandrogenism kuvakadzi chinonzi mazamu adrenal. Kuwedzera mumasero anogadzira uyerogens kunowedzera huwandu hwehomoni dzevarume. Kuwedzera kwekugadzirwa kwevarume vekodomoni zvepabonde kunogonawo kukonzerwa nekunzwa kweganda kumurume weshure-hormone - testosterone.
Hyperandrogenia muvakadzi - zviratidzo
Hyperandrogenia chirwere chinoratidzwa nekliniki, seborrhea, uye hirsutismome androgen inotarisira alopecia. Muchiitiko ichi, kuongororwa kweropa kunogona kuratidza yakakwirira kana mukati mehutano hwakanaka hwe androgens (varume vane humhononi). Ovarian shanduko, unhu hwema polycystic ovaries, zvinowanikwawo. Chinhu chinokosha, uyewo hutano hwehutano hwe hyperandrogenism kuvakadzi, hunokonzerwa nekuwedzera kwe androgens, kukanganisa kwekuenda kumwedzi, shure kwekushaya simba, maziso ekudzivirira. Hyperandrogenia mumusikana inonoka kutanga kwekuenda kumwedzi kwemakore akawanda.
Hyperandrogenism muvakadzi inoperekedzwa nekuneta. Kuchinja paganda kunosangana nekuumbwa kwemakwenzi (blackheads). Uyewo, hyperandrogenia inokonzera kuchinja kusingagadziki kunotungamirira pakuumbwa kwekrisiti shoma uye kuumbwa kwekasefu kumativi evhavha. Pakati pezviratidzo zvekunze kwezvikwata zvakakwirira zve androgens, kuputika kwemakumbo, kukura zvakanyanya kwebvudzi pamakumbo, maoko. Kuchinja kwakakomba mune mavha mavari kunogona kudzivisa kusimwa kweii, polycystosis.
Hyperandrogenism uye pamuviri
Nyanzvi dzinoshandisa hyperandrogenism ye adrenal, ovarian uye yakavhenganiswa. Hyperandrogenia yemararamiro ovari anokonzerwa nekuwedzera kwehutachiona hwebonde - testosterone, iyo inobudiswa nemaovha. Zvimwe zvinokonzera chirwere ichi zvirwere zvakasiyana-siyana zveiiii: matumbo, polycystosis. Iyo inowanzoonekwa kune vasikana vanobatanidzwa mumitambo yemasimba. Munguva yepamuviri, hyperandrogenia yeavoan genesis haisi mungozi kumucheche uye kuberekwa, uye hakudi kurapwa. Adrenal hyperandrogenism, kazhinji inokonzerwa nehutachiona kana inokonzerwa nokushayikwa kwema enzymes anobatanidzwa mukuumbwa kwe cortisol, kune ngozi kune avo vanoronga pamuviri kana kuti vane pamuviri.
Hyperandrogenia kuvakadzi panguva yekuzvitakura kunogona kutungamirira kumatambudziko anowanzotanga kusvika pakuberekwa, zvakadai sekubuda kwemaawa amniotic fluid uye basa risina simba rebasa.