Basa remwoyo yematambudziko rinongororwa nekuyera ropa. Nekusiyana kwakasiyana kwechiratidzo ichi, chirevo cheCaptopril chinorayirwa. Muchizimburo inoshandiswa kakawanda, uye kunyange iyo ndiyo nheyo yezvenguva refu yekurapa kwemishonga.
Pasinei nekupararira kwechirwere ichi, havasi vose varwere vanoziva kuti chii chinofanira kutora Captopril uye kuti inoshanda sei pamuviri zvachose.
Inoderedza kana kuwedzera kukwidzika kweKaptopril?
Iyo inotsanangurwa mishonga inosimbiswa pamusana pezvinhu zvinoshanda zvezita rimwe chete. Akabatanidzwa muboka reAAT-angiotensin rinoshandura enzyme inhibitors. Izvi zvinoreva kuti captopril inodzivirira kuumbwa kwezvinhu zvinokonzera izvo zvinokonzera kuderera kwemwenje yemidziyo yeropa. Panguva imwecheteyo, zvinoshandiswa zvinoshanda zvinokurudzira kuunganidza kwe bradykinin. Iyi enzyme inowedzera iyo mishonga yakaoma.
Nokudaro, chirwere ichi chine simba rekushaya simba, uye zviri nyore kufunga kuti chii chinokonzera kukundwa kutora Captopril - yakawedzera. Uyezve, mushonga unobudisa zvinotevera:
- Kuvandudza kushivirira kwemisungo yemwoyo kune mutoro;
- kuderedzwa kwemhirizhonga kushorwa kwemidzi yeropa kuropa;
- kuwedzera renal uye coronary blood flow;
- kuderera mumusimba wealdosterone mukugadzirwa mumadonal adrenal;
- kuwedzera mumutsetse wemukati wemwoyo;
- kuderedzwa kweropa mukati meaortic space;
- kuenzanisa kwemiganhu yekumanikidzwa kwekuroorana mumapurmonary (maduku) denderedzwa rekupararira kweropa uye atrium yakarurama;
- kuderedza kweplatelet aggregation .
Nekushandisa kwenguva refu kwechirwere ichi, ropa rinopa myocardium rinowedzera pasi pemamiriro ezvisingagumi zvinyorwa zvinokanganisa, kusimba kwehuwandu hwehutachiona, pamwe nekuwedzera kwechirwere mumasvingo emagetsi evanhu vanodzivirira, inoderedza.
Ndeipi nhare yepamusoro yeupempa inobatsira mapiritsi e capsopril?
Mishonga inowanikwa inowanzosarudzwa pakugadzirira kwenguva refu kana maitiro emakore ekurapa uye yekuchengetedza chirwere.
Chirwere ichi chinonyanya kushanda mune chirwere chehutachipembenene chechidiki kusvika pakuenzanisa, apo nhamba dze tonometer haidarika 179 ne 109 mm Hg. Art. Muchiitiko ichi, mishonga inogona kushandiswa uye seye monotherapy nekudziviswa kwekudya kwema-sodium emiti mumuviri.
Kushandiswa kwe captopril pane zvakanyanya kuwedzera simba, kupfuura 180 pa 110 mm Hg. inofanira kunge yakabatanidzwa pamwe nekushandiswa kwe thiazide diuretics (diuretics). Nhamba yemishonga inotanga kuwedzera inowedzera kusvikira yasvika pakukwirira kwayo yakabvumirwa - 150 mg yezvigadzirwa zvinoshandiswa pazuva.
Zvinogona kutaurwa kuti mishonga iyi inobatsira kubva kune chero kuwedzera kukurudzirwa, kunyanya pamwe nekubatana nemishonga inobatsira.
Ndezvipi zvinomanikidzwa zviratidzo zvekushandiswa kwe Captopril?
Mukuona kwezvakataurwa pamusoro apa, mishonga iyi isinganzwisisiki inobatsira zvose zvinyoro uye zvine mwero, uye
Mukuwedzera kune chirwere ichi, captopril inoratidzirwa mukurapa kwezviitiko zvinotevera:
- myocardial infarction nechekusiya ventricular kudzvinyirira, zvichipa mamiriro ekurwara akasimba;
- Renovascular hypertension;
- chisingagumi kana kuora mwoyo mwoyo kusakonzera
- chirwere cheshuga mellitus type 1 ine chirwere cheshuga nephropathy, kana albuminuria level isiri pasi pe 30 mg / zuva;
- cardiomyopathy yezvakabva zvakasiyana.