Adrenoblockers kana adrenolytics mishonga inononoka kana kudzivisa kutenderera kwemafungiro emagunha, i.e. ivo "vanobvisa" mabiko ari mumadziro emidziyo yeropa uye mumoyo, iyo inoita kuAdrenaline uye norepinephrine. Urongwa hwekugadzirira-adrenoblockers inowedzera zvakanyanya gore negore. Ngatiedzei kuti tione kuti ndeapi marudzi eAdrenolytics arimo, uyewo pane izvo zvinoratidzira izvo zvinoshanda.
Chii chinonzi alpha uye beta zvinodhaka-adrenoblockers?
Mhando mikuru yeadrenoblockers ndeyi:
- alpha-blockers;
- beta-blockers.
Zvichienderana nemhando yeadrenolytics inobata zvinogamuchirwa zveimwe yemhando mbiri.
Vakasiyana-siyana adrenoblockers vane fomu yakasiyana yeiyo. Saka adrenolytics inoburitswa mufananidzo:
- mahwendefa;
- ampoule nezvinogadzirisa injection;
- inodonha.
Alpha receptor blockers
Alpha-adrenoblockers mumuviri anoita zvinotevera:
- wedzera midzi miduku, nekuderedza mutoro uri pamwoyo;
- kuderedza kusvibiswa kwemuviri, kuderedza dambudziko rekudzivirira kwemitsipa yeropa uye mutoro pamutsipa wemwoyo;
- kuvandudza kushandiswa kweropa;
- kuderedza kudzvinyirira mudiki (pulmonary) denderedzwa yekuparadzirwa;
- lower cholesterol;
- kuderedza kuiswa kweglucose muropa.
Boka re alpha-receptor blockers rinosanganisira zvinodhaka zvinoshandiswa mune zvinotevera:
- arterial hypertension;
- migraine ;
- endarteritis;
- spasm yemidziyo ye retinal.
Alfa-adrenoblockers inoshandiswa zvinobudirira muhutano hwakaoma hwe prostatitis muvarume.
Kupindirana kwekushandiswa kwe alpha-blockers zvirwere:
- arterial hypotension;
- atherosclerosis;
- myocardial infarction;
- chakavanzika kana kuti hapatic insufficiency.
Muzvinyorwa zvezvakakurumbira zvema alpha-blockers:
- Dihydroergotoxin;
- Urapidil;
- Nicergoline;
- Fentolamine;
- Pyrroxane;
- Tropafen;
- Prazosin hydrochloride;
- Butyroxane.
Kuti uwane ruzivo! Pamberi pacho, zvinodhaka kubva ku-α-blocker urongwa zvakashandiswa muhutano hwepanyama mukurapwa kwevarwere vose pasina, asi sechikonzero chekutsvakurudza kwezvokurapa zvakaratidzwa kuti pane dzimwe nguva kushandiswa kwavo kunogona kutungamirira kumarwadzo emwoyo.
Beta-receptor blockers
Kutungamirirwa kwe beta-blocker zvinodhaka kunotungamirira kune zvinotevera:
- inoderedza kuchema kwomwoyo;
- kunoderedza kuwedzera kweropa;
- kupikisa kwemwoyo yemasero masero kusvika ku oksijeni nzara mu ischemia inowedzera;
- inovandudza inzwi remidziyo yeropa;
- kuumbwa kwe thrombocytes hazvibvumirwi;
- inowedzera kubuda kwe okisijeni muzviviri zvemuviri;
- basa remukati uye nhengo dzepachivande dzakasimbiswa.
Zviratidzo zvekushandiswa kwezvinodhaka pamutsara we β-blockers zvirwere zvakadai se:
- glaucoma;
- arterial hypertension;
- angina pectoris;
- cardiac arrhythmia;
- myocardial infarction;
- heart failure;
- thyrotoxicosis ;
- cardiomyopathy.
Pakati pezvinyorwa zvinoshandiswa pakushandisa zvinodhaka zvemuti uyu kune zvirwere zvakawanda, kusanganisira:
- chirwere cheshuga mellitus;
- bronchial asthma;
- COPD (chronic obstructive pesmary disease);
- kuvhara atherosclerosis.
Mutsamba ye beta-blockers yechizvarwa chitsva, zvinodhaka:
- Cordanum;
- Anaprilin (Propranolol);
- Metoprolol;
- Bisoprolol (Concor);
- Nebilet (Nebivolol);
- Betaxolol (Lokren);
- Aptin;
- Betazprin;
- Esmolol et al.
Zvinokosha! Kunyange zvazvo mamwe mishonga-adrenoblockers inogona kutengwa mumafarimasi asina mishonga, asi inofanira kushandiswa maererano nemirairo yechiremba, semigumisiro yakakomba inogona kuwanikwa panzvimbo yekurapa.
Hybrid adrenoblockers
Kune boka rinodhaka remishonga rinozviratidza pachavo panguva imwechete se alpha-adrenolytics uye beta-adrenolytic zvinodhaka. Aya ndiwo adrenoblockers, akadai se:
- Labetol;
- Procodolol.