Triiodothyroxine kana T3 inonzi hormone inogadzirwa nehutachiona gland pachishandiswa tetraiodothyroxine (T4), nemhaka yekuparara kwayo. Iyo inobudiswa mubhuku duku, 10% chete, zvisinei iyo inonyanya kushandisa biologically inoshandiswa yegoutocrine chimiro.
Kazhinji kuongororwa mabasa ehutachiona yakakosha kunofanirwa kuongorora pachena T3 - rudzii rwehomoni uye chii chinotarisirwa, kuziva zvishomanana. Zvisinei, chimiro che triiodothyroxine chinonzi inonyanya kukosha kwesimba metabolism mumuviri.
Chii chinonzi hormone T3 inopindura?
Icho chinyorwa chezvinhu zvinenge zvichinyorwa ndeye tetraiodothyroxine, ine 4 iodine molecules. T4 inonzi hormone yakaderera, inobudiswa nehutachiona hukuru muhuwandu (anenge 90%).
Mushure mekuparadzanisa imwe iodine molecule kubva ku tetraodothyroxine, T3 inoumbwa. Iyi hormone inowanika katatu kupfuura yeT4, inoshandiswa pamagadzirirwo emagetsi ekuparadzanisa, kukurudzira basa rekutya, kusanganisira basa reropi. Chaizvoizvo, triiodothyroxine ndiyo inonyanya kukurudzira yezvinhu zvose zvinokosha mumuviri.
Kamwe T3 inopinda muropa, inosungira mapuroteni. Vanoita basa rokutakura, vachiendesa hormone kune nhengo nenyama, umo pane kudiwa nokukurumidza. Iyo yakagadzirirwa triiodothyroxine mumutsananguro inonzi inowanzo.
Humwe huwandu hwehomoni inoramba iri muropa risina kuvhara mapuroteni, ndiyo iyi T3 isingabhadharwi. Iko kunongororwa kunofungidzirwa kuti ndiyo inogadzirisa muongorori wechinhu chetachiona, sezvo triiodothyroxine isina kubhururuka inonyanya kushanda uye inobudisa izvo zvataurwa pamusoro apa zvinowanzoitika.
Free thyroid hormone T3
Ma laboratori akasiyana-siyana anosimbisa maitiro avo ezvakagadziriswa ezvinhu zvakabvunzwa. Vanovimba nenzira yekuverenga maitiro ayo, zviyero zvechiyero uye kunzwisiswa kwemidziyo inoshandiswa.
Nokuda kwakanyanya immunochemiluminescent analyzers, hutano hunotsanangurwa huri pakati pe 2.62 kusvika 5.69 nmol / l. Muhupo hwezvinhu zvisinganyanyi kunzwisisika, chikamu chepamusoro chechimiro chinowanzoratidzwa zvishoma, 5.77 nmol / l.
Nemhaka yei iyo hormone T3 yakasununguka yakawedzerwa?
Kusiyanisa kubva kune dzimwe nguva tsika dzakanaka zvinowanzoratidza zvirwere zvakasiyana-siyana kana zviitiko zvenguva zvemuviri zvinokonzerwa nekurapa.
Zvikonzero zvakakosha zvekutakura hormone T3 pasina:
- kuwandisa kwehutano hwemuviri hwakakurudzirwa;
- imwe ichangobva kupera hemodialysis course;
- utachiona husina kunaka (kwenguva pfupi) mushure mekuberekwa;
- myeloma pamwe chete nehana yakakura ye immunoglobulin G;
- subacute kana acute thyroiditis;
- chisingarapiki chirwere chechiropa;
- nephrotic syndrome mukukudzwa kwe glomerulonephritis;
- HIV utachiona;
- choriocarcinoma;
- hyperestrogenia;
- porphyria ;
- diffuse toxic goiter;
- kugamuchirwa kwemahymoni e thyroid, zvakasiyana-siyana zvekudzivirira pamuviri, methadone, cordarone.
Izvo zvinoda kukurumidzirwa kutarisana ne-endocrinologist kana hormone T3 isingasunungurwi yakasimudzwa - kurapwa kwakatanga munguva, inobatsira kudzivisa zvinetso zvezvirwere zvakarondedzerwa, kudzivirira kukura kwezvakaipa zvinosvibisa uye metastasis.
Nei hormone T3 isingabhadharwi?
Izvo kuderera kwehuwandu hweusina kukwana tri-thirotoxin haisi ngozi sekuwedzera kwayo. Zvikonzero zvikuru zvezviitiko zvakadaro
- kusagadzikana kwebasa rinodiwa;
- chirwere chepfungwa;
- kudya kunoderera muprotheni;
- hypothyroidism ;
- kuporeswa kubva kune chirwere chakaipa;
- kurapwa nemitemo, anabolic, anti-inflammatory drugs, antithyroid drugs, steroids;
- kupembera kwemazuva ano kwakagadziriswa.