Chimiro chebilirubin muzvitsva

Mumazuva okutanga ehupenyu hwechecheche, mavara echteric yeganda uye mavara emucheka anooneka angaonekwa-chirwere chemuviri chechecheche chinowanikwa. Inokonzerwa nekuti mumazuva ekutanga ehupenyu fetal hemoglobin yeropa rinoparara, zvichichinja zvinowanzoitika, uye chibereko chekuparara kwe hemoglobin ibheri. Munguva yekuparara kweHemoglobin, isina kuratidza bilirubin inoumbwa, iyo inosungira puroteni iri muchiropa uye inoshandurwa kutungamira bilirubin. Izvo zvisina kujeka bilirubin isingasviki, haisi kunyorwa nemukoro, yakanyatsosvibiswa, yakanyanyiswa ne bile.

Chimiro chebilirubin muropa rechecheche

Chimiro chekunyoresa bilirubin hachina ma25% evanhu bilirubin. Mukuora kwe fetal hemoglobin, huwandu hwehuwandu hwebilirubin hunowedzera, husina nguva yekuzvisunga ne albumin. Iyo yakareba yepamusoro iri pazuva rehupenyu hwechitatu, shure kwaizvozvo inoderera kwevhiki mbiri. Munguva iyi, hutachiona hwehuviri hunoonekwa uye hunopera, izvo, kusiyana nehutachiona, hunoenda pasina tsanangudzo uye hahudi kutarisirwa.

1. Kana mwana akaberekerwa mumbilical cord ropa, muzinga webilirubin muzvitsva zvinowanzosvika kusvika 51 μmol / l.
2. Pazuva rokutanga rehupenyu, kuwedzera kwehuwandu hwebilirubin haufaniri kuva yakakwirira kupfuura 5.1 μmol / l kweawa. Panguva imwe chete, kuwedzera kukuru muhuwandu hwebilirubin muvana vakakwegura zvakakwana kusvika pa256 μmol / L kusvika mumazuva 3-4 ehupenyu, mukutanga vana - vasati vasvika 171 μmol / l.
3. Ivhareji yepamusoro yebilirubin mumazuva ekutanga eupenyu kazhinji haapfuuri 103-137 μmol / l, uye kuwedzera kunokonzerwa nedzimwe nhengo bhalirubin.

Kana chirwere chemajeri chisina kuchinja mamiriro ose echecheche, ruvara rwemuti nemasese, pamwe nekukura kwechiropa uye chepleen, ganda rine chine marangi, uye jaundice inopera pasina kurapwa pavhiki 2-3 yehupenyu. Degrees of physiological jaundice:

• 1 degree (icteric ruvara rwechiso uye mutsipa chete);
• 2 digita (icteric ruvara rwemukati wepamusoro wemuviri kusvika kumigumo);
• 3 digita (icteric tsvuku yechiso, trunk uye kumusoro kwemaoko nemakumbo);
• 4 degree (kukwana muviri wose muvaraidza weicteric, kusanganisira tsoka uye mabhushi).

Zvikonzero zvinowedzera bilirubin muzvitsva

Mukuwedzera kune utachiona hwehupenyu, kunewo chirwere chinonzi jaundice muzvitsva, umo pachavawo nepamusoro bhalirubin uye ruvara rwechinyakare rweganda uye mucous membrane. Aina dze pathological jaundice:

1. Hemolytic. Nemhaka yekuwa kwemasero matsvuku eropa mukurwisana pamusoro peboka reropa kana Rh inhengo pakati peamai nevana, zvirwere zvegeneti - microspherocytosis, sickle cell anemia.
2. Kuora mwoyo - nekuda kwechiropa kukuvara ne congenital hepatitis, cytomegalovirus, toxin.
3. Kugadziriswa - munyaya yezvisina kuchena mu enzyme system uye kusungirirwa kwehuwandu hwebilirubin.
4. Mechanical - muzviitiko zvekuputsika kwekubuda kwebi nokuda kwekuvharwa kweguruvladder kana chiropa chechiropa pamwe neukama hwavo husina, semuenzaniso, atresia.

Pamusoro pekushandiswa kwebilirubin muropa (zvinopfuura 324 μmol / l), inopinda muropa reuropi-echokuita uye inoita sehupfu muuropi hwechecheche (nuclear nyuundice). Izvi zvinokonzera kushaya encephalopathy nekunonoka kwezvinhu zvose zvisinganzwisisiki, kusava nehanya, kushungurudzika uye kunyange kufa kwomwana. Zvinetso zve nuclear nyuundice zvinogona kuora mitezo uye paresis, kutadza mupfungwa uye matsi.

Kurapa kwehuwandu hwakawedzera hwebilirubin muzvitsva

Physiological jaundice haiwanzodi kurapwa, nekutaura kworudzi rweganda kunogona kushandisa phototherapy, umo chiedza chezuva chinokurumidza kusunga bilirubin. Nechirwere chinonzi jaundice, kuwedzera pane phototherapy, chiremba kazhinji anongorayira kubudisa detoxification uye kunyange kutengesa kuwedzerwa ropa.