Estradiol ihurmone yevakadzi inobva kuestrogen yeboka, iyo inonyanya kubudiswa nemashizha (mune nhamba shomanana inoshandiswa nemadonal glands). Hondo yehomoni ye-estradiol pakati pevakadzi inopesana zvichienderana nechikamu chekuenda kumwedzi. Kubudiswa kwe-estradiol kunosimudzirwa nekubudisa mahomoni emucheka wepituitary. Muchikamu chedu, tinodzidza kuti chii chinokanganisa hormone yekadzi isradiol uye chii chiri ngozi kana zvikanganiso zvichibva kune zvayo.
Iyo hormone estradiol - chii chinokonzera?
Sezvatotaurwa, kubudiswa kwekureruka (LH) uye follicle kukurudzira (FSH) mahomoni mumutambo wepituitary inokurudzira kugadzirwa kwe-estradiol nemashizha. Basa guru re isradiol ndiyo inokonzera follicle kukura uye kukura kwebasa rinoshanda re endometrium. Penguva yekuvhara, kuwanda kwemukati kwemukati we endometrium kunofanira kuva 10 mm. Kushaikwa kwe-estradiol kunopesana nekukura nekutsvaga kwehupenzi hukuru - saka, ovulation haigone kuitika. Kukura kwemabasa ekupedzisira endometrium kuchavewo kusinganzwisisiki. Mumamiriro ezvinhu akadaro, kunyange dza rakabudirira rinoberekwa haigoni kuiswa mumadziro echibereko uye kuchava nekuparara pamuviri panguva yekutanga.
Kutaura nezvemabasa eestradiol, hatigoni kutadza kutaura kuti ndiye iye anoita mukadzi akanaka. Pasi pemubatiro wehomoni yevakadzi isradiol, chimiro chevakadzi chinoumbwa (chifukidzo chikuru, chiuno chine tsvina uye kuchinja kusina kuchena kusvika muhudyu), ganda rinova rakanaka uye rakasvibiswa, uye rinodzivirira bvudzi kukura munzvimbo dzakare dzevarume (chiso, chifuva, makumbo, mimba).
Kuongororwa kwe estradiol muvakadzi
Kuongororwa kweestradiol kunoitwa neveousous sampling blood in a blank stomach. Nhamba yeestradiol hormone inowanzosiyana zvichienderana nechikamu chekufamba. Saka, inotanga kuumbwa kubva pamazuva okutanga ekuenda kumwedzi (mu follicular phase, chiyero che-estradiol chinobva 57-227 pg / ml). Pakati pepakati pemhepo, iyo isradiol index ndiyo yakareba (vasati vasvika ovulation yezinga ye estradiol iri mumakero 27-476 pg / ml), iyo inotora maawa 24-36 ichakonzera kuparara kwehuputi uye kutanga kwekuvhunga. Mushure mekuvhara, mazinga eestradiol akadzikiswa zvakanyanya. Saka muchikamu chekutevera iri 77-227 pg / ml. Kuwedzera kwezinga re estradiol pakati pevakadzi muchitatu chechitatu chekuenda kumwedzi kunoratidza kutanga kwekuzvimba.
Panguva yekuzvitakura, uwandu hwewesradiol muvakadzi hunowedzera kuwedzera, huchikwanisa kuwaniswa huwandu asati aberekwa. Mushure mokuberekwa mukati memazuva 4-5, uwandu hweedradiol muropa inodonha zvikuru.
Nhamba yeestradiol iri pasi pemaitiro evakadzi inogona kuva nezvikonzero zvinotevera:
- kusvuta;
- mhuka yezvirimwa;
- unopinza kuora kwekurema;
- kukanganisa kushandiswa kwemakemikari epabonde;
- kukundwa kwetambo yepituitary;
- kuita basa rakawandisa.
- yakawedzera prolactin mazinga.
Munguva yekuguma kwemwedzi, uwandu hweedradiol hwakaderera uye huri pakati pe19.7-82 pg / ml. Kuwedzera huwandu hwehomoni iyi panguva yekuguma kwemwedzi kunogona kutaura pamusoro pezvirwere zvinotyisa zve mavha mavari.
Nhamba yeestradiol muvarume
Mumuviri wenyama, isradiol inobudiswa muzvinyorwa zvematete uye adrenal glands mune zvishoma. Kazhinji uwandu hweizvi
Saka, takaongorora maitiro ezvinyorwa zve-estradiol mumukadzi, pamwe chete nezvikonzero zvekuwedzera uye kuderera. Nokushayikwa kwe-estradiol mumudzimai wechikadzi unokonzerwa nekutanga kuenda kumwedzi, kuvhiya uye kupiswa kwemazuva, hypo-andinorrhea, kugamuchirwa kweanorogue yakagadzirwa kunoratidzwa. Nokudaro, kugadzirira 17-beta estradiol (estradiol e2) yakafanana neyakasikirini isradiol uye inowanikwa sechinhu chinotapira, chinopisa mafuta, spal nasipiritsi. Mushonga unogona kungotorwa mushure mekutaurirana chiremba.