Hemoglobin uye erythrocytes, izvo zvave zvichiita mabasa avo, zvinotarisirwa kugadziriswa muropa. Somugumisiro wezviitiko zvakadaro, bilirubin inoumbwa - se-yellow-green pigment. Icho chiratidzo chechiropa uye spleen, nzira dzemagetsi. Nokudaro, tsika inowanzogamuchirwa yebilirubin muropa revakadzi inofungidzirwa seimwe yenheyo huru pakuita maongorori ekuongorora zvirwere zvakasiyana-siyana zvehepatological, endocrine uye zvirwere zvekudya.
Izvo zvinowanzoitwa bilirubin yose mukuongorora ropa mune vakadzi
Kuumbwa kwebilirubin kunotanga nemasero matsvuku eropa ane hemoglobin uye kutakura okisijeni kune zvose zvinyoro zvinyoro uye nhengo dzomukati. Erythrocytes, vanopedza nguva yavo, vanopinda spleen uye marora, pamwe neechiropa, uko nzira dzekuparadzwa kwavo dzinoitika. Somugumisiro wekuparara kwemasero aya uye hemoglobin component, bilirubin inosunungurwa. Kutanga, haisi yakananga uye inotyisa kune muviri, saka pachiropa parenchyma inopa mari yakakosha yemakemikari iyo inoshandura chikamu ichi kuti iite zvakananga bilirubin. Izvo zvakasungwa zvakanyanyiswa mu bile, mushure mokunge inopinda mumukumbo uye inowanzosunungurwa pamwe chete nemhuka.
Bilirubin munyaya iyi inosanganisira urobilin uye stercobilin, idzi pigments, iyo inopa humwe hunhu hwemuti nemucheka, zvichienderana. Nokudaro, apo kusungirirwa kwekombani iri pasi pekufungisisa kuwedzerwa, ruvara rwekuyerera runochinja zvakare. Urini inowana ruvara rudema, uye mhuka dzinosviba chena.
Chimiro chekuzara kana chizere chelikububin muropa revakadzi chibva kune 3.4 kusvika 17.2 μmol / l. Kana pane nhoroondo yezvirwere zvechiropa, nhoroondo yemazuva ehutachiona hwehutachipatachi, hutsva hunogona kubva kubva pa8,5 kusvika ku20,5 μmol / L, huchiteverwa nekusimudzira.
Zvakakosha kuziva kuti huwandu hwakatarwa hunofungidzirwa huripo kana mitemo yose ichicherechedza pakupedza kuongororwa:
- Usadya mushure mekudzidza. Zviri nani kurega kudya kwemaawa gumi nemaviri, asi ngatitii nguva inenge maawa mana.
- Usadya kofi uye chero zvinwiwa zvine caffeine usati wopa ropa.
- Usanwe hepatoprotectors , choleretic magadzirira, mishonga inonatsa ropa (aspirin, heparin, warfarin).
- Usatye nenzara, usadya kudya usati watsvakurudza.
Nguva yakanakisisa yekuendesa ropa inopa ropa inenge inenge yepfumbamwe mangwanani.
Ndezvipi zvinowanzoitwa bilirubin inopa ropa rakawanda mukati mevakadzi?
Iyo enzyme-yakasungwa ne-yellow-green pigment kana bilirubin pamwe ne glucuronic acid, yakagadzirira kubudiswa kubva mumuviri, haifaniri kudarika 4.3 μmol / l (mune vamwe vakadzi - kusvika ku7,9 μmol / l ine zvirwere zviripo zvehutachiwana) -25% yehuwandu hwebilirubin.
Izvozvo zvishoma zvakananga yellow-green pigment muropa zvinotsanangurwa nekuti iyo, sekutonga, inokurumidza kubviswa kubva mumuviri kuburikidza nechepamusoro pamwe chete nemafuta uye bile.
Ndezvipi zvinowanzoitika kune zvisina kufanira bilirubin muropa revakadzi?
Iyo yakatsanangurwa ikakiti mune fomu isina kumira (chikamu chisina kujeka), seyakatotaurwa, inonyangadza yemuviri uye inotarisirwa kugadziriswa pakarepo mumasero eropa.
Muitiro wekusaziva kana kusununguka bilirubin muropa revakadzi haufaniri kudarika 15.4 μmol / l. Nokudaro, pigment isina kuvhara inenge 70-75% yehuwandubin mu plasma.
Zvinonakidza kuti chikamu chiduku chisingaenzaniswi, chinonziwo mahwendefa asingasviki, hachisi chinhu chimwe chete, asi chimiro chakaoma chemukati ne albumin. Kuti uone kuti yakajeka yakadini mu laboratori inokwanisika chete mushure mekuparadzwa kweiyo molecule uye kushanduka kwayo kuva mamiriro ekudzivirira mumvura.