Alpha-fetoprotein - iyo inonzi puroteni, iyo inobudiswa mudumbu rekudya uye chiropa chemwana asati aberekwa. Basa rayo rinosanganisira kutengesa kwezvibereko kubva kuna amai kusvika pamucheche. Nenzira, iyi ipuroteni inochengetedza embryo kubva pakuramba masimba emuviri wemuviri. Muhupenyu hwose hwekufambisa kwechecheche, kuwedzera kwe AFP panguva yekuzvitakura kunowedzera zvose muropa re fetal uye muropa raamai. Mumwedzi wokutanga wekudzivirira, alpha-fetoprotein inobudiswa nehutano hwemashizha, uye kubva pamasvondo mashanu uye nguva yose yegestation nguva iyi purotini inobudiswa ne fetus pachayo. Iyo yakasungirirwa yepamusoro ye AFP muropa inowanika panguva yevhiki 32-34, uye inotanga kuderera zvishoma nezvishoma.
Kuongorora kwe AFP panguva yekuzvitakura, sekutonga, kuitika pavhiki 12-14 yezwi. Ichi chiratidzo chinodikanwa pakusarudza kusakanganiswa kwekuvandudzwa kwecheche pachirwere chechiromosomal, kushungurudzika kwekuvandudzwa kwehurongwa hwekutya, pamwe nekukanganisa mukuumbwa nekuvandudzwa kwezviviri zvemukati. Nokudaro, vanachiremba vakanyatsocherechedza kuiswa kwepuroteni iyi mu serum yevakadzi vane pamuviri.
AFP - inowanikwa panguva yekuzvitakura
Tafura iri pasi apa inoratidza AFP panguva yekuzvitakura.
Zvinofanira kuonekwa kuti index yeAAPP mukudzivirira, pamwe chete nevakadzi vasina pamuviri nevarume vakuru, vangave nekuregerera, kukosha kwayo kunobva kubva kuna 0.5 kusvika ku2,5 MoM (kureva kuwanda kwemuviri). Kuparadzana kunoenderana nehuwandu hwehutachiwana, pamwe chete nemamiriro ezvinhu eropa sampling.
AFP panguva yekuzvitakura
Kuwedzera kwehuwandu hweAIDS panguva yekuzvitakura kunogona kuva chiratidzo chekuyeuchidza, munyaya iyi zvakakosha kuongorora zvirwere zvinotevera zvekuberekwa:
- necrosis yechiropa, iyo inoitika mushure mehosha inotapukira yaamai;
- chinomarara chetsvo;
- umbilical hernia;
- anencephaly;
- spina bifida;
- kusagadzikana kwemuviri wepamuviri mudumbu;
- zvimwe zvisiri izvo.
Mukuwedzera, AFP yakakwirira mumadzimai ane pamuviri inogona kuitika nehuwandu hwekuzvitakura.
A low index ye AFP panguva yekuzvitakura inogona kuonekwa mumamiriro ezvinhu anotevera:
- trisomy 18;
- Down syndrome;
- bladder skidding ;
- kunonoka pakukura kwe fetus;
- hydrocephalus;
- kufungidzira pamuviri;
- kuparadzaniswa kwepasipo;
- kufa kwe fetus.
Dzimwe nguva kuderedza AFP panguva yekuzvitakura chiratidzo chekusaziva nguva.
AFP uye kuongorora katatu
Kuongorora kweAIDS AFP panguva yekuzvitakura kunopa zviratidzo zvakatendeseka kana kuongororwa kunoitwa pamwe chete nekutsvakurudza kune ultrasound, kugadzirisa kwezinga reesriol isina mahwende uye mahomoni anokonzera. Kuongororwa kwezvose zvinoratidzwa zviratidzo, pamwe ne AFP uye hCG panguva yekudzivirira kunonzi "kuongorora katatu".
Ropa paAfP panguva yekuzvitakura inowanzobviswa kubva mumutsipa. Iko kuongorora kunofanira kutorwa mangwanani mangwanani musina chinhu chisina chinhu. Kana musi wekutsvaga kuongororwa uku uchiri kuruma kana, somuenzaniso, kudya kwekudya kwemafuro, saka inofanira kudarika maawa 4-6 mushure mekudya kwekupedzisira, zvisinei kuti chigumisiro chichava chisina kutendeka.
Mune imwe yenharaunda yeA AFP mukudzivirira