Alkaline phosphatase - chii chichaongororwa?

Munenge mishonga yose yevanhu nhengo dzeboka dzine boka re enzymes - alkaline phosphatase. Iyo yakanyanyogadziriswa yayo iri mu-placenta, bone bone, chiropa uye bile ducts. Basa rinowedzera re phosphatase rinogona kuratidza kuvapo kweimwe zvirwere zvinoda kurapwa nokukurumidza.

Chii chinonzi alkaline phosphatase?

Tichifunga nezve enzyme iyi zvakadzama, zvakakosha kutaura pamusoro pebasa re alkaline phosphatase mu metabolism yemafuta, izvo zvinoda miviri yealkaline, saka zita re enzyme. Zvisinei, kune marudzi akawanda e enzyme, zvichienderana nenzvimbo yaro:

• hepatic phosphatase (yakanyanya kukura muvanhu vakuru);
• pfupa (yakakwirira pane vana);
• placental (high concentration mumadzimai ane pamuviri);
• alkaline intestinal phosphatase;
• renal (iyi alkaline phosphatase muropa haina kuonekwa, nokuti haipindi mairi kusiyana nemamwe marudzi).

Analysis for alkaline phosphatase

Muzviitiko zvakawanda uye kuonekwa kwezvimwe zviratidzo, mutsara inorayirwa, alkaline phosphatase iyo inogona kuwedzerwa kana kuderera, iyo inotungamirira kumagumo akakodzera. Ita izvi kuongororwa:

1. Muhutano hwakaoma hwechiropa samples .
2. Kudzora zvirwere zvepfupa panguva yekurapa.
3. Kana murwere achitora mishonga inokurudzira kuonekwa kwecholestasis (kukura kwe bile, kutyora kwekugadzirwa kwayo uye kugadzirwa).
4. Kana pane chimiro chezviratidzo zvakadaro: kuora mwoyo, kubvongodzwa kwemasese, misi yakaipa, kurutsa, jaundice, kurasikirwa kwesimba nekukurumidza kupera.

Chii chinonzi alkaline phosphatase inoratidzira muropa test?

Mubvunzo weiyo alkaline phosphatase inoratidze ndeyekuda kune avo vasingazivi nezvechirevo ichi kana kuti vari kuitisa kuedza kwekutanga. Nhamba ye enzyme inorayirwa kakawanda nokuda kwekuongororwa kwezvirwere zvemapfupa, chikwata chebhiriyari uye chiropa. Kuwedzera kwealkaline phosphatase kunogonawo kutaura pamusoro pekuvapo kwezvirwere zvinotyisa: oncology ye testis, lymphogranulomatosis kana maitiro akaipa muuropi. Zvisinei, kune dzimwe nhamba dzenyaya umo kuongorora nekugadzirisa kwakabva pamigumisiro yakawanikwa inofanira kuitwa zvichifunga zvimwe zvikamu.

1. Nekushaiwa kwekinc muzvokudya, kuwedzera kwe enzyme kunogona kuwedzera, nokuti ichi chinhu chikamu che phosphatase.
2. Kuitisa kuongororwa kwevana kuti vaone zvinetso ne excretion ye bile hazvina maturo, saka, sekutonga, chiyero che 5'-nucleotidase inorayirwa.
3. Nokuda kwekutonga, kuongororwa kwe phosphatase kunofanira kuitwa kwete kamwe kamwe pavhiki, nekuda kwekubviswa kwayo kubva muropa mumazuva 3-4.
4. Chikonzero chekuwedzera kwevanhu vakwegura ndechekuderera mu bone.
5. Kuchengetedza kuongororwa kune vadzidzisi vemapoka ekutanga uye matatu eropa, zvakakosha kufungisisa kuti chiyero chepachivi phosphatase chinogona kuwedzerwa mushure mekutora kudya kwemafuta, saka, shanduro yeropa inofanira kuitwa panzvimbo isina chinhu.

Alkaline phosphatase - the norm

Zvakakosha kuziva kuti alkaline phosphatase iri muropa, chimiro chevakadzi, varume nevana - chakasiyana. Zvinyorwa zve enzyme hazvirevi kungoita zvepabonde bedzi, asiwo pazera, izvo zvinodawo kuverengwa. Kusvikira kumakore gumi nematanhatu, uwandu hwealkaline phosphatase maitiro nguva dzose, uye shure kwezera iri inotanga kuderera. Vakadzi vane zvinotevera:

• kusvika kumakore gumi nemasere - zvishoma: 46 masayiti per litita; mukuru: 119 U / l;
• kubva pamakore makumi maviri namashanu kusvikira kune makumi mashanu (45) - zvishoma pa: 32 maundi / l; zvizhinji: maundi zana pamatare;
• kubva pamakore makumi mashanu kusvika kune makumi matanhatu nemakumi mashanu - zvishoma: zviyero makumi matatu / l; zvakanyanya: 115 U / l;
• kusvika kumakore makumi manomwe - inowanzo i 135 maundi / litita;
• mushure memakore makumi manomwe, chimiro che 165 maundi / litita.

Kune zvikonzero zvakawanda nei chiratidzo ichi chingawedzera zvikuru, asi kwete nekuda kwekuvapo kwezvirwere:

• munguva yekubereka kwomwana;
• munguva yeHS;
• pamberi peevitaminosis;
• nekuda kwekushaya zvokudya zvinovaka muviri;
• nemhaka yekushingaira kwepanyama.

Muvarume, chiratidzo ichi chiri pamwero wepamusoro kupfuura chechikadzi nemaminiti 20-25 / l, uye nezera, sevakadzi vanobuda. Chimiro chealkaline phosphatase muropa revanhu:

• kubva pamakore 17 kusvika ku30 - kusvika kumakamuri zana / litita;
• kubva pamakore makumi matatu kusvika kune makumi mashanu (45 kusvika kune makumi maviri nemashanu) - kusvika pamasero 120 / litita;
• kubva pamakore makumi mana nemasere kusvika makumi mapfumbamwe nemaviri - kusvika pamakamuri makumi matatu nematanhatu;
• kubva pamakore makumi mashanu kusvika kune makumi manomwe - kusvika kumakamuri 145 pamatare;
• kubva pamakore makumi manomwe - kusvika pa1 190 maundi / litita.

Muvana vaduku, kuongororwa kwe enzyme kwakakwirira kudarika kune vanhu vakuru uye hazvirevi pane zvepabonde. Mukuyaruka, mutsauko uyu unowonekwa nekuda kwemararamiro akasiyana-siyana emagadzirirwo emagetsi mumuviri. Saka, chirevo chevana nevechiri kuyaruka:

• muzvitsva uye mumavhiki maviri ekutanga ehupenyu: 83 - 248 units / l;
• kubva masvondo maviri kusvika pagore: 122 - 469 maundi / l;
• kubva pamakore gumi kusvika ku13: 129 - 417 units / litre.

Alkaline phosphatase inowedzera - zvinorevei?

Chii chinogona kureva kana alkaline phosphatase ichiwedzerwa, unofanirwa kuziva kuti ubatsire nyanzvi mukurongeka kwakarurama uyezve kurapwa. Zvimwe zvikonzero zvekukwirira kwechikafu chepalphatase zvichabatsira kunzwisisa kwete chete chikonzero chekuoneka kwezviratidzo zvisingafadzi, asiwo kuratidza kuvapo kwezvirwere zvine chimiro chekupedzisira. Izvi zvinopisa nyanzvi yepamusoro.

Alkaline phosphatase inowedzera - zvikonzero

Pazvinotsanangura zvikonzero zvekuwedzera kwealkaline phosphatase, mapoka akawanda anonyanya kuonekwa, iyo yekutanga inobatanidza nekusaita mukati meropa uye bile ducts:

• matombo mumidha;
• cholestasis;
• chirwere chechiropa, chinogona kuitika nekuda kwehupfu hunouraya uye kana uchitora mishonga;
• primary cholangitis;
• chiropa cheropa;
• hepatitis (autoimmune uye viral);
• infectious mononucleosis;
• jaundice (kazhinji mumadzimai anotora CCD ne progesterone uye zvinyorwa zveesrogen).

Kuchinja kwepathological mu bone bone, umo alkaline phosphatase inowedzera:

• Paget's disease (kuderera kwemapfupa, kukanganisa kwavo uye kuderera);
• kuwedzera mumagadzirirwo emagetsi munguva yekuporesa kwezviputsi;
• kunyorera kwemapfupa (calcium salts, vitamine uye phosphoric acid zvakarasika, izvo zvinotungamirira kukudzikisa uye kuderedza mapfupa);
• Osteosarcoma uye metastases zvakapinda mumapfupa emapfupa.

Zvimwe zvirwere uye zvinokonzera kana yakawedzera alkaline phosphatase muropa, isingabatanidzi hutano husina kunaka uye hutachiona hwehutano:

• chirwere chemuviri wepamuviri;
• myocardial infarction;
• chirwere chendocrine chinokonzerwa nehutachiona phosphoric metabolism uye calcium metabolism - hyperparathyroidism;
• pamuviri;
• doro kudhakwa;
• kurapwa nemishonga inenge ine hepatotoxic effect.

Alkaline phosphatase inowedzera - chii chandinofanira kuita?

Kana kuongororwa kwakanyorwa kuwedzera mu-alkaline phosphatase, chinhu chekutanga chakakosha ndechokubvisa chinokonzera chikonzero chakakonzera izvi kusvetuka. Somuenzaniso, ane zvirwere zvechiropa kuti adzorere mabasa ayo, aratidze kushandiswa kwemishonga yehupatoprotector uye kupora kudya kwakakodzera. Zvose zvinotorwa zvinofanira kurongerwa nachiremba uye zvinoitwa pasi pekutarisa kwake.

Alkaline phosphatase inoderedzwa - zvinorevei?

Kana zviyero zvakaratidza kuti alkaline phosphatase inoderedzwa, izvi zvinogona kuratidza kuti chirwere chinotyisa chiri kukura mumuviri. Kuti uite zvakakwana kuongororwa, mamwe maedzo haakwani uye iwe unoda kuongorora kwakakwana kwevanyanzvi vakadaro:

• hematologist;
• Chiremba;
• nyanzvi mune zvirwere zvinotapukira;
• gastroenterologist;
• general practitioner.

Alkaline phosphatase yakaderedzwa - chikonzero

Muchizhinji chezviitiko, kuderera kwechikafu chesiphatase kunoitika nekuda kwezvikonzero zvinotevera:

• anemia in severe form;
• kushaya kupera mumuviri we magnesium uye zinc;
• chirwere chezvechirwere chechimondroplasia (pasi pemapfupa emapfupa, izvo zvinokonzera kusuruvara);
• kuwedzerwa ropa guru;
• kushayikwa kweB- C uye mavitamini ;
• placental insufficiency;
• dystrophy nekuda kwekushayikwa kweprotheni muzvokudya - kwashiorkor;
• hypothyroidism (low level of thyroid hormone production);
• cretinism;
• sc oga;
• hypophosphatase (kukanganisa kunokonzerwa nekuchera minera yepafu tissue).

Alkaline phosphatase inoderedzwa - chii chaunofanira kuita?

Kana kuongororwa kunoratidza kuti zvakadzama alkaline phosphatase, saka zvinokuvadza kuwana chikonzero iwe pachako, saka unoda kuti utaure kamwechete neanyanzvi. Kutanga, inogona kuva chiremba uyo achaona kuti imwe nyanzvi yomuzivi inofanirwa kuenderera mberi sei. Mushure mokupfuura kuongororwa kwakawedzerwa, chiremba anofanira kuwana chikonzero chekutapudzwa kweAAP uye kuronga kurapwa kana kuitumira kune nyanzvi mumunda wehosha inoonekwa.

Alkaline phosphatase pamuviri

Munguva yemakore ekugwinya, chiyero chealkali phosphatase chinogona kuva chakakwirira kunze kwekuvapo kwezvirwere zvinokonzera kusvetuka mumwero we enzyme muropa. Izvo zvose pamusoro pekuumbwa kweparcenta, umo, sezvinonyatsozivikanwa, yakanyanya kukanda ye enzyme. Izvo zvakakosha panguva yekudzivirira kugara uchicherechedza kuchinja kwezinga re alkaline phosphatase, kuitira kuti usakanganwe nguva iyo kuwedzerwa kana kuwedzerwa kuwanda kwe enzyme kunoratidza zvinetso zvehutano.

Kurera huwandu, sezvatakatoona, zvinogona kuratidza zvinetso nechiropa uye bile ducts, pancreas, bone system. Kana iyo alkaline phosphatase inoderedzwa, zvino izvi zvinogona kuva chikonzero chekusava nekunyanyisa kwemavara kana kushaya simba, izvo zvinogona kuita kuti nyaya igumise kuberekwa. Izvi zvinogona kuitika nokuti placenta munharaunda yakadaro haikwanise kupa mwana wacho fetus nezvose zvinodiwa zvinovaka muviri.