Digoxin imishonga inowanzoshandiswa pakurapa kwezvirwere zvemoyo, kazhinji mune mahwendefa. Anoshandiswa kune boka rezvemasikirini emwoyo glycosides - mishonga yemishonga, ine cardiotonic uye antiarrhythmic effect.
Kemikari yakagadzirwa uye kurapwa kwemahwendefa Digoxin
Izvo zvinoshanda zvechirwere Digoxidine ndiyo imwechete digoxidine, yakasarudzwa kubva pamashizha emuti, digitalis woolly. Zvimwe zvikamu zvepepa yepeti yezvinodhaka ndeyokuti:
- silicon dioxide colloidal;
- gelatin;
- magnesium stearate;
- talc;
- simbi kubva muchibage;
- lactose monohydrate.
Kana inotorwa nemuromo, mishonga yacho inonyatsopindira muhutachi hwepamuviri uye inoona kuti inopera maawa anenge 2-3 mushure mekudya. Izvozvo zvinotapira zvinotora kwemaawa matanhatu. Mushonga wacho wakanyanyisa kunyanya urine.
Pasi pesimba rekushanda kwechirwere ichi, zvinotevera zvinowanikwa:
- kuwedzera mune simba remyocardial muscle contractions (positive inotropic effect);
- kuwedzera mukudengenyeka kweropa;
- kuderera muhuwandu hwezvipikiso zvemutsipa wemwoyo;
- kuderedza kwechigarire systolic uye gumbo diastolic yakawanda yemwoyo;
- kuderedza kudiwa kweokisijeni kwemyocardium;
- chiito chinopesana (kuburikidza nekuderedza uwandu hwemagumisiro kuburikidza neshoko reatrioventricular uye kuwedzera nguva yakakodzera yekugadzirisa);
- vasodilator effect (pamwe nekupindirana pamusana pemwoyo wekukundikana );
- mild diuretic effect;
- kupera kwekufema kwekufema;
- kuderera muEdema, nezvimwewo.
Zviratidzo zvekushandiswa kwemishonga inonzi Digoxin
Zviratidzo zvikuru zvekushandiswa kwemushonga Digoxin ndizvo zvakadai:
- kusingaperi kwemwoyo kukanganisa kwe II, III uye IV makirasi anoshandiswa (sechikamu chemishonga inodhaka yakaoma);
- tachycardic form of atrial fibrillation;
- paroxysmal atrial fibrillation;
- paroxysmal supraventricular tachycardia.
Kuteerera nemero yekushandisa mapiritsi Digoxin
Kana iri mishonga yose iri muboka remwoyo glycosides, kuyerwa kweDigoxin kunosarudzwa nokungwarira nechiremba achienda, achifunga nezveunhu humwe hwemuviri wemurwere, kusimba uye maitiro ehutachiona hwehutano, uye nemararamiro emagetsi emagetsi.
Semuenzaniso, rimwe remitemo yekutora mishonga pomufurati inosanganisira kugadzirirwa kwaDigoxin mune chikamu che 0.25 mg 4-5 pane zuva rokutanga rekurapa, uye mumazuva anotevera - 0.25 mg matatu kamwe kamwe pazuva. Munyaya iyi, kugamuchirwa kunofanira kuitwa pasi pekutarisirwa kwechiremba.
Mushure mekudiwa kwekuchirapa (kazhinji mushure memakore manomwe kusvika ku10), kuyerwa kwechirwere kunoderedzwa, kushandiswa kwemishonga yemishonga inorayirwa kushandiswa kwenguva refu. Kusarudzwa kwejojo dzepravenous, sezvinotonga, zvinotarisirwa chete kana pakaoma kukanganisika kwepakati.
Migumisiro Yechipfuva yeDogoxin:
- nausea;
- kurutsa;
- stool disorders;
- kusava nenzara;
- headache;
- chizoro;
- kushushikana kwehope;
- heart failure;
- kuwedzera kubuda ropa;
- itching;
- urticaria;
- general weak;
- kuneta, nezvimwewo.
Kupindirana kwekushandiswa kwe Digoxin:
- kudhakwa nemwoyo glycosides;
- acute myocardial infarction;
- angina akadzikama ;
- Wolff-Parkinson-White syndrome;
- atrioventricular block;
- bhardycardia ane zviratidzo zvikuru zvekuchirapa;
- acute rheumatic heart disease;
- mitral stenosis uye vamwe.