Kusvikira iye zvino, munhu anenge aine mafungiro ehutachiona mweya yakaipa kwazvo. Maererano nehuwandu hwemashoko, pane pasi redu pamusoro pemamiriyoni makumi matatu evanhu vanotapukirwa, avo vanoda chirwere chekutapukirwa kweHIV.
Pane mushonga weHIV here?
Sezvinozivikanwa, mishonga inorwisa mishonga inoshandiswa kurwisana nechirwere ichi, icho chinoderedza kukura uye kuwedzera kwehutachiona, uye kudzivirira kuiswa kwayo mumasero ane utano. Zvinosuruvarisa, hapana yemishonga inokwanisa kukwanisa zvachose munhu wehutachiona, sezvo hutachiona huchikurumidza kugadzirisa kuhutano uye hunochinja. Kunyangwe mafungiro uye ane maitiro ekutora mishonga inobatsira kusarega kurasikirwa nekuwedzerwa hupenyu kwemakore anopfuura gumi. Nokudaro, inoramba ichitarisirwa kuti rimwe zuva vachawana kana kuuya nemishonga yeHIV inoporesa kusvika kumugumo.
Mishonga iripo
HIV ine retrovirus, ndiko kuti, utachiona hune RNA mumasero ayo. Kukurwisa, zvinodhaka zvinoshandiswa kurwisana nehutachiona hweHIV pane imwe nzira yekuita:
- Inhibitors ye reverse transcriptase.
- Protease inhibitors.
- Inhibitors ye integrase.
- Inhibitors ye fusion uye kupinda mukati.
Kugadzirira kubva kumapoka ose kunoderedza kukura kwehutachiona pamatanho akasiyana-siyana ehupenyu hwayo. Zvinopesana nekuwedzera kwe HIV uye kushandura maitiro avo enzymatic action. Muitiro remazuva ano rezvechiremba, mishonga yakawanda yevanodhakavira mairi kubva kumakwikasi akasiyana anoshandiswa panguva imwechete, nokuti kurapa kwakadaro kunonyanya kubudirira mukudzivirira kuchinja kwechirwere kumushonga uye kubuda kwekuchengetedza (kugadzikana) kwechirwere.
Iye zvino nguva inotarisirwa apo vachagadzira mushonga wehutachiona hweHIV, huchava nehutachiwana hwekirasi yega yega, kwete kungosimbisa kukura kwerwere, asiwo nokuda kwekufa kwahwo kusingagoneki.
Mukuwedzera, pakurapa kwehutachiona, zvinodhaka zvisina kuchinja zvakananga masero ehutachiwana anoshandiswa, asi anobvumira muviri kuti utarame nemigumisiro yaro uye kusimbisa masimba emuviri.
Vachawana mushonga weHIV here?
Masayendisiti pasi rose ari kuramba achivandudza mishonga mitsva yekutapukirwa kweHIV. Funga nezvevakanyanya kuvimbisa.
Nullbasic. Iri zita rakapiwa kune mishonga yakagadzirwa nesayendisiti kubva kuIsi Institute for Medical Research muguta reKlinsland (Australia). Iyo nyanzvi inofunga kuti, nemhaka yekushandurwa kweprotini zvisungo zvehutachiona pasi pekuita kwechirwere, HIV inotanga kurwisana. Nokudaro, kwete chete kukura uye kuwedzera kwehutachiona hunomira, asi pakupedzisira rufu rwemauto atova nehutachiona hunotanga.
Mukuwedzera, paakabvunzwa kana mushonga uyu uchauya kubva kuHIV, muumbi wacho anopindura anokurudzira - mumakore gumi anotevera. Muna 2013, miedzo yezvikara yatotanga, uye mamwe majekiseni emakiriniki anorongwa kuvanhu. Imwe yemigumisiro yakabudirira yeongororo ndiyo kushandurwa kwehutachiona
SiRNA. Yakagadzira mishonga iyi yeHIV nevanosayendisiti veAmerica kubva kuYunivhesiti yeColorado. Mamokoko ake anovhara maitiro emagetsi anosimudzira kuwedzera kwemasero ehutachiona, uye anoparadza mapuroteni ayo. Panguva ino, tsvakurudzo inoshanda iri kuitwa pamwe nekuongororwa pamashamba emukati, iyo yakaratidza kuti mamolekoro emuviri wacho zvachose haasviki uye anobvumira kuti majekiseni eRNA ehutachiwana atapudzwa kwemaawa anopfuura matatu.
Nyanzvi dzesayunivhesiti dzinoti kuwedzera kwekugadzirwa kwemichina yekugadzirwa kwemishonga yakarongwa kuchabudirira kurwisa kwete chete HIV, asiwo AIDS.