Non-steroidal anti-inflammatory drugs - urongwa

Nonsteroidal anti-inflammatory drugs (NSAIDs) iboka remishonga inoshanda ine zvinotevera antipyretic, anti-inflammatory and analgesic effect.

Nokudaro, mishonga iyi inobatsira kuderedza marwadzo, fivha uye kuputika. Chiito chavo chakavakirwa pamusana pekudzivirira kwevamwe enzyme, kuburikidza iyo kushandiswa kwezvinhu zvinokonzera kupisa kwemuviri kunoitika mumuviri. Kusiyana ne glucocorticoids (hormonal agents), iyo yakaita iyo yakafanana, marwadzo asina-steroid mishonga haayati yakadaro yakawanda yezvinhu zvisina kunaka.

Mukuwedzera, dzimwe NSAIDs dzinopesana-aggregation effect (dilution, kukudziridzwa kwehutachiona hweropa), uyewo zvirwere zvekudzivirira zvirwere (immunosuppressive effect).

Zviratidzo zvekushandiswa kweNSAIDs

Muzhinji, kwete-steroidal anti-inflammatory drugs inoshandiswa muzvirwere zvakaoma uye zvisingaperi, pamwe nekuputika uye kurwadziwa. Ngatitangei mazita ematambudziko, apo mazano anotevera eboka rakapiwa anokurudzirwa:

• osteoarthritis;
• rheumatoid arthritis;
• gout;
• musoro, migraine ;
• fever;
• zvirwere zvepfungwa;
• dysmenorrhea;
• renal colic;
• metastases yemapfupa;
• postoperative pain syndrome;
• kuvhiringidza arthropathy.

Rondedzero yevasina-steroidal anti-inflammatory drugs

Nyaya yemazuva ano isiri-steroidal anti-inflammatory drugs ikozvino yakazara. Dzinosarudzwa maererano nekemikari yakasikwa uye chimiro chechiitiko chacho. Uyewo maitiro akasiyana-siyana easiri-steroidal anti-inflammatory drugs akaparadzaniswa: mahwendefa, capsules, mafuta, mafuta, suppositories, injectable solutions, nezvimwewo.

Funga nezvemashoko makuru eNSAIDs:

1. Salicylates:

• Aspirin;
• Diflunisal;
• lysine monoacetyl salicylate.

• Indomethacin;
• Sulindak;
• Ichi ndicho eelander.

• Diclofenac ;
• Aceclofenac.

• Ibuprofen;
• Ketoprofen;
• Tiaprofenic acid;
• Naproxen;
• Flurbiprofen;
• Fenbufen;
• Fenoprofen;
• Nabumethoni.

• Lornoxicam;
• Tenoxicam;
• Piroxicam;
• Meloksikam.

• Rofecoxib;
• Nimesulide;
• Celecoxib.

Kubva pamagadziro anopiwa pamusoro pekuita, zvinodhaka zvakadai seKetorolac, Ketoprofen, Diclofenac, Indomethacin zvinoshanda zvikuru. Iyo yakanakisisa inopesana nekuvhiringidza zvinhu Indomethacin, Flurbiprofen, Diclofenac uye Piroxicam.

Zvakakosha kuziva kuti kwete-steroidal anti-inflammatory drugs inotengeswa pasi pezita rakasiyana-siyana yebhizimisi. Nokudaro, kana uchitenga mushonga mune imwe mishonga, pakutanga kwezvose, munhu anofanirwa kubhadhara zita remarudzi ose.

Nonsteroidal anti-inflammatory drugs zvechizvarwa chitsva

Nonsteroidal anti-inflammatory drugs zvechizvarwa chitsva zvinoshanda zvakasarudzwa uye zvinoratidza basa rakakwirira pane rienzanise nevakatangira. Muchiitiko ichi, pasina mimwe migumisiro inobva pamatumbo emimba.

Vamiriri vemishonga mitsva yeboka reNSAID ndiwo oxycam. Mukuwedzera kune zvakasarudzwa pamusoro apa, zvinodhaka izvi zvinoratidzwa nekuwedzera kwehafu yehupenyu, nekuda kwekuti chiito chechirwere ndechei nguva yakareba. Dambudziko rega roga remishonga iyi ndeyekudhura kwayo.

NSAIDs dzinewo zvinopesana nazvo:

• erosive uye ulcerative zvipembenene zvepachiviri chepamuviri;
• kutyorwa kwechiropa neitsvo;
• cytopenia;
• pamuviri;
• kunyanya kusawirirana.