Mazuva ano haasi-steroidal anti-inflammatory drugs anoshandisa imwe yenzvimbo dzekukudzwa mumishonga. Ivo vane antisgesic uye antipyretic effect, nokukurumidza bvisa kuzvikudza, kurega kuputika uye kuderedza marwadzo ekurwadziwa. Nemhaka yezvinhu izvi zvinowanzoshandiswa zvikuru mukurapa zvirwere zvakawanda.
Zviratidzo zvekushandiswa kwevasina-steroidal anti-inflammatory drugs
NSAID dzemazuva ano dzinowanikwa nenzira yejojo, suppositories, mahwendefa, capsules, gel uye mafuta. Inowanzoshandiswa kune zvirwere zvisingaperi kana zvinotyisa, zvinosangana nekutambudzika kwakanyanya nekuputika. Kazhinji kazhinji vanorayirwa kuti:
- osteoarthritis;
- gout;
- rheumatoid arthritis;
- Reiter's syndrome ;
- dysmenorrhea;
- migraines and headache;
- metastases yemapfupa;
- fever;
- postoperative pain syndrome;
- renal colic
Zvisizvo zvisingaiti zvekuzvarwa kwechizvarwa chitsva
Zvinyorwa zvekare zvisingagadziriswi zvisiri izvo zvinoshandiswa zvinoshandiswa pane isoforms ye cyclooxygenase: kuchengetedza enzyme (COX-1) nekuputika enzyme (COX-2). Izvo enzyme yekudzivirirwa yakadzingwa navo, iyo yakaderedza kuderera mumabasa ekuchengetedza kwemukoma membrane yemudumbu uye zvirwere zvakasiyana-siyana zvegumbo rose remavhu akabuda. Asi kwete-steroidal-anti-inflammatory drugs zvechizvarwa chitsva vanoita zvinopesana - iyo enzyme yekuputika inodzingwa kune imwe huru. Vongai izvi:
- Kuzvidzivirira kwemuviri mukurapa kwakasimba;
- migumisiro inowanzoitika zvishoma;
- mishonga inoshanda zvakanyanyisa.
Kugadziriswa kwechigadziriswa chechizvarwa chitsva hakubatsiri COX-1. Vose zvavo vanozivikanwa nehupamhi hwekuchengeteka kwemuviri womunhu. Dzimwe mimwe migumisiro mushure mekushandiswa kwavo kunogona kuitika. Asi izvi zvinongoratidzwa chete kana kudya kwechirwere chitsva chisina-steroidal anti-inflammatory inotora nguva yakareba. Munyaya iyi, haafaniri kukwaniswa. Mune zvimwe zviitiko, iwe unongoda kusarudza chirwere chakakwana.
Ndeapi mishonga inobatana nemishonga yemazuva ano isiri steroid?
Oksikam - zvigadzirwa zvemadhimoni asina-steroidal. Iboka iri remishonga rinoratidzika nekuwedzera kwehafu yeupenyu. Nokuda kweizvi, chiito chechirwere mumuviri chinowedzera, izvo zvinobvumira kuderedza kuwanda kwekutora mishonga. Oksikamy dzakatorwa sechikonzero chekugadzirwa kwemishonga yemazuva ano isiri steroid.
Muenzaniso wechizvarwa chitsva cheNSAID ndeye Xefokam. Izvi zvinodhaka zvine unyanzvi hwakakura hwekutsvaga. Simba rake rekuita rinogona kuenzaniswa naMorphine. Iko kungofanana neapiate-kufanana nehutachiona hwehutachiona hwehutano uye hunodhaka hahuiti.
Uyezve itsva isiri-steroidal anti-inflammatory drugs ndeyi:
- Nimesulide - yakashandiswa kurapa arthritis uye vertebrogenic kurwadziwa shure. Mushure mekutungamira kwaro, kupisa kunonyangarika, hyperemia, kutonhora kunowira, uye kufamba kunovandudza.
- Celecoxib chirwere chinoderedza mamiriro omurwere ane arthrosis uye osteochondrosis. Kurwisana nekurwisana nekuputika uye
anobvisa zvachose marwadzo ekurwadziwa. - Meloksikam - mishonga ine antipyretic, anti-inflammatory uye yakarongedzwa zvakajeka. Inogona kutorwa kunyange kwenguva yakareba. Iyo inobudiswa neL Meloxicam mune mahwendefa, mhinduro yejojo, mafuta nemafuta.
Nhamo yega yemishonga isingashandisirwi ndeyekuti haitungamiri pakugadzirisa zvakakwana mu osteochondrosis, arthrosis yejoints uye arthritis . Mukurapa kwezvirwere izvi, zvinongodiwa chete nokuda kwekununurwa kwekutambudzika uye / kana kubviswa kwekuputika.