Kwose immunoglobulin E (Ig E) chinhu chinokosha chekusateerera kwemashoko uye chiratidzo chekugadzirisa zvinokonzerwa nemhando yakadaro. Chirwere cheG Ig chinoshandiswa kuongororwa zvirwere zvakasiyana-siyana uye helminthiases (atopic dermatitis, urticaria, atopic bronchial asthma).
Ndeipi iyo inowanzozivikanwa nayo immunoglobulin E?
Kwose immunoglobulin E inodzivirira zvakasiyana-siyana zvekunze kwemuviri wemuviri kuburikidza nekushandiswa kwemasero masero uye plasma zvinokonzera kukuvadza kuita. Kusiyana nemamwe marudzi e-immunoglobulins (D, M, A, G), inokonzera kukurudzirwa kwemasukisi kune zvose zvinokonzera, izvo zvinogonesa kukurumidza kukura kwehutano husingaiti. Ig E inobudiswa munzvimbo. Izvi zvinonyanya kuitika mu submucosal mashizha emasikisi akasiyana-siyana, ayo anoramba achitarisana nemamiriro ekunze. Inogona kuva:
- ganda;
- toni;
- adenoids;
- kupemha tract;
- chirwere chepamuviri.
Kana chirwere chacho chichipinda mumuviri womunhu, chinosangana nemamwe maitiro e-immunoglobulin E. Iyi nzira inosangana nekubudiswa kwemasero e histamine uye zvinhu zvakasiyana-siyana zvinoshandiswa pamakumbo ayo Ig E akagadziriswa.Vokupinda munzvimbo inoshandiswa kunotungamirira kukurudzirwa kwemazuva ano kunopisa kupisa. Rinozviratidza mufananidzo:
- rhinitis;
- dambudziko guru;
- bronchitis;
- severe rash.
Inogonawo kuumba sarudzo inogadziriswa (inowanzo mukana wevanaphylactic shock).
Sei uye kuongorora sei immunoglobulin E?
Kuongororwa kwejena immunoglobulin E inoshandiswa pakuonekwa kwezvirwere zvakasiyana-siyana zve-allergenic uye yekuonekwa kwechirwere chepachirwere. Kuti uongorore hutano, hazvina kukwana kungoziva kuti g Ig yose yakasimudzirwa muropa. Zvakakosha kuziva kuti causative allergen uye mamwe maitiro anorwisana nayo. Asi nhamba yeG Ig E inokubvumira kukurumidza kusiyanisa zvirwere zvinokonzerwa nehutachiona kubva kune zvirwere zvinotapukira zvinenge zvakafanana nezvirwere zvechirwere, uyewo kuziva zvirwere zvinokonzera zvirwere uye kusarudza kurapa kwakakwana.
Usati watora immunoglobulin E, hakuna kudzidziswa kwakakosha kunokosha. Izvo zvakakosha chete kuti usadye usati waongorora. Kazhinji kacho, kuongorora kwakadaro kwebhroreta kunorayirwa kuti:
- scabies ;
- ganda rashes;
- itching
Angioedema uye urstaria inogara isiri yemazuva ano haisi zviratidzo zvakananga zvekugadzirisa kwema immunoglobulin E, sezvo iyo isiri yomuviri.
Chii chinoitika kuwedzera kweGG concentration?
Nyaya yekugadziriswa kwemajoni emuviri weE immunoglobulin E ndiyo ropa rose serumusi. Zvikamu zvakakura zveG Ig E mukati mazvo zvinoratidzwa apo:
- Pollinosis;
- zvokudya zvekudya;
- asthmatic bronchitis;
- urticaria;
- Stevens-Johnson syndrome ;
- Quincke's edema;
- bronchial asthma.
Kuwedzerwa kwehuwandu hwehuwandu hwema immunoglobulin E hunogara huchitaridzwa ne atopic dermatitis, chirwere cheSerum, chirwere cheLyell uye zvinodhaka zvemishonga. Dzimwe nguva chirongwa cheG Ig chepamusoro kupfuura chenguva dzose, kana munhu ane helminthic infestation, chirwere
Zviratidzo zvekududzirwa kwemigumisiro ye Ig Ig kuongorora?
Low immunoglobulin E inoratidza kuti munhu ane ataxia-telangiectasia syndrome kana kuti akawana immunodeficiency. Izvo zvakaguma zvekutsvaga zvakajeka here? Izvi hazviregi kutarisa kwezviratidzo zvezvirwere. Somuenzaniso, 30% yevarwere vane zvirwere zvepopopi vane Ig E mazinga mukati mekugara. Mukuwedzera, vamwe vanhu vane chirwere chinonzi bronchial asthma vanogona kuva nekunzwisisika kune rimwe chete. Somugumisiro, ivo vanowanzofanana Ig E vanogona kugara vari mukati mehutano hwakakwana.