Zvigadzirwa zvemushroom mushonga, ane chimiro chekugona kurwisa mamwe majekesheni, anonzi antibiotics. Pamusana pezvakaitwa zvakagadzirwa nehupenyu uye kusavapo kwekukanganisa kwevanhu, beta-lactam mishonga inorwisa mabhakitiriya inowanzoshandiswa mukurapa antimicrobial, iyo yava ndiyo nzira huru yekurapwa kwezvirwere.
Iyo nzira yekuita kwe beta-lactam antibiotics
Nhengo huru yemishonga iyi ndeyekuvapo kwebheteri-beta-lactam, iyo inosarudza basa ravo. Icho chiito chikuru chinangwa chekusika hukama pakati pemakemikari emakemikari anokonzerwa nekuumbwa kwemberi yekunze, nemamolekemu e penicillin nemamwe maantibiotic agents. Masangano akasimba anoita kuti kudzvinyirirwa kwebasa rezvirwere, kupera kwekukura kwavo, izvo zvinotungamirira pakufa kwavo.
Urongwa hweBeta-lactam antibiotics
Kune zvikamu zvina zvakakosha zvemishonga inorwisa mabhakitiriya:
1. Penicillin , iyo inogadzirwa zvekutsinhanisa kwemhando dzakasiyana dzepentillium fungi. Maererano nemavambo avo ivo vakasikwa uye semi-synthetic. Boka rokutanga rakakamurwa kuva bicillins uye benzylpenicillins. Muchipiri, ma antibiotics e beta-lactam akapararira:
- Ampicillin, inozivikanwa senzira yekuwanda kwemaitiro;
- Oxacillin, Methicillin - madhiragi, mhedzisiro yaro inotarisa zvishoma;
- ureidopenicillins, iyo inoparadzwa ne beta-lactases (Piperacillin, Azlocillin);
- Inonzi penicillas, inosanganisira beta-lactamase inhibitors (tazoctam, clavulanic acid), iyo inodzivisa kuparadzwa kwemajeri nemaabhakitiriya ( Amoxiclav , Unazin, Sulacilin, Augmentin).
2. Cephalosporins inokonzerwa nefungus Cephalosporium inopesana ne beta-lactamase kupfuura yekare boka. Kune mabhakirini akadai e-beta-lactam:
- Cephaloridine;
- Ceforaxime;
- Cefotaxime ;
- Cefoxytin.
3. Monobactam , iyo inosanganisira Azrethon. Iyi mishonga ine chikamu chiduku chekuita, sezvo isingabatsiri mukutonga kwe strepto- uye staphylococci. Saka, zvinorayirwa, kunyanya kurwisana ne-gram-negative fungi. Aztreons inowanzopiwa navanachiremba kana vasina kuvhiringidza penicillin.
4. Carbapanemes , iyo vamiririri vemu Meropenem uye Impenem, ndevamwe nzira dzinenge dzine ruzivo rwakawanda kwazvo rwezvibereko. Meropenem inoshandiswa kunyanya kurwisa zvirwere zvinotapukira, uyewo kana pasina hunovandudzwa mukutora mamwe mishonga.