Wati wakambofunga here kuti nei zvinodhaka zvakagadzirwa zvakafanana zvinowanzova nemari yakasiyana? Imodium yakakurumbira inodhura zvikuru kupfuura Loperamide, uye mushure mokunge mishonga iyi yose yakanyatsofanana, ine chinhu chimwe chinoshanda. Zviratidzo zvekushandisa kwaLoperamide zvichave zvakafanana, uye mutengo waro uchashamisa iwe. Chii chinobatwa?
Zviratidzo zveLoperamide Hydrolochromide
Mukunyorwa kweImodium neLoperamide, chimwe chete chinonzi Loperamide hydrochloride, zviratidzo zvekushandiswa ndezvizvi:
- ruru diarrhea ;
- asingagoneki mararamiro;
- chimiro chemuviri mushure mushure mekuvhiya.
Zviratidzo zvakadaro zveLoperamide zvinokonzerwa nekuti chinhu ichocho chinopedza simba pamusana unotapira mumatumbo uye nekuda kweizvi kuchengetwa kwechigaro kunoitika. Loperamide inotaura nezvekugadzirira opioid uye inobva piperidine. Iyo inodzivisa chiito chezvinyorwa zvemukuchi izvo zvinonamatira maopiates saka zvinokonzera kuti sphincter iite chibvumirano, uye motokari inoshanda kushandura. Pakutanga, chirwere chacho chaishandiswa kurapa gastroenteritis uye marudzi akasiyana-siyana ekuputika kwemukati, mazuva ano inoshandiswa kunyanya kurwisa manyoka.
Loperamide yakawanikwa nevasayendisiti veBelgium muna 1969 uye kubvira ipapo yakakurudzirwa zvikuru mumusika pasi pezita rokuti Imodium. Mukufananidza, munyika dzakawanda, zvakafanana zvechirwere chakafanana zvakagadzirwa zvakasunungurwa. Pamba mhuri Loperamida-Akri zvachose zviratidzo zvekushanda. Asi zvakadaro zvimwe zvezvinodhaka izvi zvakasiyana, zvinoreva - chiyero chekunatswa kwezvinhu zvinoshandiswa, chiyero chekutonga mukugadzirwa uye kuwanikwa kwezvidzidzo zvitsva pachigadzirwa. Izvi zvinonzwisisika, nokuti kuwedzera kwekugadzira, mari yakawanda inogona kugovera kumibvunzo yakadaro.
Somuenzaniso, mumakore ekuma1990, Johnson naJohnson, avo vakanga vari kukurudzira Imodium, vakabvisa chirwere ichi kubva mumusika nekuda kwevakafa vakafa muPakistan. Zvadaro kubva pakushandiswa kweImodium, vana 19 vakatambura. Zvinyatso zvinyatsoongorora zveloperamide pane izvi hazvina kuguma uye iyi mhinduro yakagadziriswa. Ichokwadi ndechekuti muvana uye, zvikurukuru, vacheche, piperidine uye zvigadzirwa zvayo zvinotungamirira kupisa kwemisumbu yemukumbo kusvikira kuora mitezo. Sezvo mutemo, chiitiko chakadaro chinowanikwa muvana vasati vava nemakore maviri, munguva yekukwegura kwakadaro kudarika hakuiti. Uye, zvisinei, kushandiswa kwemishonga, kusanganisira loperamide, munyika dzakawanda inobvumirwa chete kune vana vanopfuura makore matanhatu, uye muAustralia, vana vanopfuura makore gumi nemaviri.
Dosage uye kutungamirirwa kweLoperamide
Nekurapa kwehutachiona hwehutachiona, vanhu vakuru vanopiwa chirwere chekutanga cheLoperamide muwandu we 4 mg, iyo inofananidzwa ne 2 capsules yemishonga. Mune ramangwana, tora 2 mg yemishonga mushure mechigaro chimwe nechimwe, kana ichiramba ichiva munyoro, mvura. Kana chiitiko icho chigaro chiri chimiro, kana murwere ane kuvimbiswa , kushandiswa kwemapiritsi eLoperamide kunofanira kubviswa.
Kurapa kwekugara kwenguva refu, vanhu vakuru vanorayirwa 2 mg yemishonga 1-2 nguva pazuva kusvikira mamiriro acho akadzikama.
Vana vane makore anopfuura 6 vakasarudzwa pachavo uye vanobva pauremu hwemuviri wemwana. Therapy
Nhamba yezuva rose yeLoperamide kuvanhu vakuru ndeye 16 mg, yevana 6-8 mg.
Mukurapa kwezvinonzi "mararamiro evanhu vanofamba," chirwere chinotyisa uye chirwere chinotyisa, chirwere chacho chinotarisirwa maererano nechirongwa chakafanana nekurapa chirwere chakanyanya.
Nehanya, Loperamide inotarisirwa kukanganisa kwechiropa neitsvo. Mishonga iyi inopesana:
- ane pamuviri;
- vanaamai vanoyamwisa;
- vana kusvika kumakore matanhatu.