Kukwegura inzira isingadzivisiki inobata munhu wese, achiyerera zvishoma nezvishoma uye achienderera mberi. Zvisinei, pane chirwere umo izvi zvinokura zvakakurumidza, zvinopinda nhengo dzose uye maitiro. Ichi chirwere chinonzi progeria (kubva muchiGiriki - nguva isati yakwegura), inonyanya kushamisika (1 nyaya yevanhu 4 kusvika ku8 mamiriyoni), munyika yedu mune mamiriyoni akawanda ezvakatsauka. Kune miviri miviri mikuru yekufambira mberi: Hutchinson-Guilford syndrome (progeria yevana) uye Werner's syndrome (kufambira mberi kwevakuru). Nezvekupedzisira tichazotaura munyaya yedu.
Werner's Syndrome - chakavanzika chesainzi
Werner's syndrome yakatanga kurondedzerwa nechiremba wechiGermany Otto Werner muna 1904, asi kusvika zvino, kufambira mberi kunoramba kuri chirwere chisingazivikanwi, zvikurukuru nekuda kwechiitiko chisingawanzoitiki. Zvinonyatsozivikanwa kuti iyi inorwarisa chirwere chinokonzerwa neine gene mutation, iyo inotora nhaka.
Kwemazuva ano, masayendisiti akazvitsanangurawo kuti Werner's syndrome ndiyo chirwere chinokonzera kuporesa. Izvi zvinoreva kuti varwere vane progeria vanogamuchira pamwe chete kubva kuna baba namai mumwe anomeless gene ari mu chromosome yechisere. Zvisinei, kusvikira ikozvino hazvibviri kutsigira kana kuramba kufungidzirwa kuburikidza neve genetic analysis.
Zvikonzero zvekufamba kwevanhu vakuru
Chikonzero chinonyanya kukonzera chirwere chekukwegura kusati chasarudzwa. Dambudziko remajini rinowanikwa mumagadzirirwo emagetsi evabereki vemurwere ane hupenyu husingaiti hunochinja muviri wavo, asi kana hubatanidzwa huchitungamirira kune chinotyisa, kurambidza mwana kutambura mune ramangwana uye kusati kwasvika kubva muupenyu. Asi chii chinotungamirira kuzvinhu zvakadaro zvakasiyana-siyana zvisati zvajeka.
Zviratidzo uye nzira yechirwere
Kuratidzwa kwokutanga kwaMerner's syndrome kunoitika pakati pemakore gumi nemana (18 dzimwe nguva gare gare), mushure memakore ekuyaruka. Kusvikira panguva ino, vateereri vose vanokura zvakanyanya, uye mumitumbi yavo zvirongwa zvekupera simba kwehupenyu hwose hunotangira. Sezvo mutemo, pakutanga vevarwere vanove vhudzi, iyo inowanzobatanidzwa nevhudzi rakasakara. Iko kune kushanduka kwakajeka paganda: kuoma, wrinkles , hyperpigmentation, ganda rinomisa, rakanyarara.
Pane zvirwere zvakasiyana-siyana zvinowanzoperekedzwa nekukwegura kwepanyama: cataracts , atherosclerosis, moyo wehutano hwehutano hwehutano, osteoporosis, zvakasiyana-siyana zvezvakaipa uye zvinotyisa zvinopisa.
Matambudziko eDokocrine anowanikwawo: kusabatwa kwezviratidzo zvepabonde zvekare zvekuenda kumwedzi, sterility, izwi rakakwirira, utachiona husina simba, shuga yekushuga isingawaniki neshuga. Atrophy mafuta mavara nemisungo, maoko nemakumbo zvisingatauriki zvishoma, kufamba kwavo kwakanyanyisa.
Yakaratidzwa kuchinja kwakasimba uye zviso zvepiso - zvinotariswa, chinhu chinoputika, mhino inowana kufanana nemuromo wemhiri, muromo unoderera. Pazera remakore makumi matatu nemakumi matatu, munhu ane munhu mukuru anofambira anotarisa semurume ane makore makumi masere. Varwere vane Werner's syndrome havawanzorarama makore makumi mashanu, vachifa kanowanzobva nekenza, kurwisa kwemwoyo kana kurohwa.
Kurapa kwevanhu vakuru
Zvinosuruvarisa, hapana nzira yokubvisa chirwere ichi. Mishonga inongororwa chete pakubvisa zviratidzo zvinotanga kuitika, pamwe nekudzivirira zvirwere zvinogadzirisa zvinokonzera pamwe nekuwedzera kwadzo. Nekuvandudzwa kwepurasitiki, kwakave zvakare kukwanisa kururamisa zviratidzo zvekunze kusati kwakura.
Parizvino, miedzo inowanikwa mukurapa kwaMerner syndrome nemasero emukati. Inoramba ichitarisirwa kuti migumisiro yakanaka ichawanikwa munguva yemberi iri pedyo.